Tuesday, May 24, 2016

How To Better Identify Patients That Do Not Benefit From Prophylactic ICD Therapy?

Citation: Ian Mann MBBS MRCP, Amit Kaura MBChB, Paul A Scott DM MRCP

The implantable cardioverter defibrillator (ICD) has been demonstrated to improve survival by reducing sudden cardiac death (SCD) in patients with a low left ventricular ejection fraction (LVEF). Randomised trial data suggest that this mortality reduction is not constant among those implanted with a device, and has raised the significance of non-sudden cardiac death (non-SCD) as an important mode of death predicting limited benefit from ICD therapy. In this review article we explore the role of non-SCD and the risk prediction models that may aid identification of low LVEF patients unlikely to gain significant benefit from ICD therapy.

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