Non-Invasive ECG Mapping To Guide Catheter Ablation

Citation: Ashok J. Shah, MD, Han S. Lim, MBBS, PhD, Seigo Yamashita, MD, Stephan Zellerhoff, MD, Benjamin Berte, MD, Saagar Mahida, MBChB, Darren Hooks, MD, Nora Aljefairi, MD, Nicolas Derval, MD, Arnaud Denis, MD, Frederic Sacher, MD, Pierre Jais, MD, Remi Dubois, PhD, Meleze Hocini, MD, Michel Haissaguerre, MD

Since more than 100 years, 12-lead electrocardiography (ECG) is the standard-of-care tool, which involves measuring electrical potentials from limited sites on the body surface to diagnose cardiac disorder, its possible mechanism and the likely site of origin. Several decades of research has led to the development of a 252-lead-ECG and CT-scan based, three dimensional electro-imaging modality to non-invasively map abnormal cardiac rhythms including fibrillation. These maps provide guidance towards ablative therapy and thereby help advance the management of complex heart rhythm disorders. Here, we describe the clinical experience obtained using non-invasive technique in mapping the electrical disorder and guide the catheter ablation of atrial arrhythmias (premature atrial beat, atrial tachycardia, atrial fibrillation), ventricular arrhythmias (premature ventricular beats) and ventricular pre-excitation (Wolff-Parkinson-White syndrome).